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Merck KGaA, Darmstadt, Germany), MS settings of the screening method used in 20202023 were switched to high-mass detection (m/z 7003,000) and the ESI-L LCMS Tuning Solution (Agilent Technologies) was used for calibration, whereas, in the screening method used in 2024 the data acquisition range was changed to m/z 1003,000, and a sodium iodide solution was used for MS calibration

doi: 10.1016/j.jtho.2019.12.109 70 ReadyNEOttPAHellmannMDZugazagoitiaJHannCLde BraudFet al

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Inositol works at the cellular level and is thought to prevent the formation of cancer and may even shrink pre-existing cancers

Elevated RRM2 levels also correlate with MYCN expression levels and poorer survival outcomes in NB patients (47)