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Cycling and breaks Given the unknowns about long-term continuous use, many researchers implement cycling protocols

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It is then infused into the abdominal cavity and maintained for a specified time, with the objective of preventing and treating malignant tumor implantation and metastasis ( Meanwhile, during intravenous drug administration for cancer patients, platinum-based anticancer drugs may be released into the air through vaporisation, leading to indirect exposure or inhalation of platinum agents through the skin or respiratory routes ( 5 Reproductive toxicity and genotoxicity of platinum drugs Platinum drugs, which are frequently employed chemotherapeutic agents, are extensively utilised in treating a range of malignancies, including ovarian, bladder, lung and liver cancer, among others

doi: 10.1016/j.cmet.2013.03.013 27 de AngelisM.GarrutiG.MinerviniF.BonfrateL.PortincasaP.GobbettiM