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Consume excessive alcohol Have immune dysfunction Are older adults (see below for more on this) Have gastrointestinal disorders

Systemic neurological conditions also drive chronic muscle spasms: multiple sclerosis (MS), peripheral neuropathy, amyotrophic lateral sclerosis (ALS), and restless legs syndrome all disrupt the normal nerve-to-muscle communication pathway, producing involuntary contractions that can affect the entire body

doi: 10.3389/fimmu.2018.02134 Received 09 June 2018 Accepted 29 August 2018 Published 20 September 2018 Volume 9 - 2018 Edited by Fabio Malavasi, Universit degli Studi di Torino, Italy Reviewed by Benjamin Bonavida, University of California, Los Angeles, United States

You should continue using these additional or alternative contraception methods for at least four weeks after starting Mounjaro, and for four weeks following any dose escalation