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These observations suggest a significant contribution of CYPOR to NFT-induced Nrf2 activation in the HepG2 model, but also indicate that other cellular flavoprotein reductases are likely to be involved in the formation of the NFT radical anion and its subsequent activation of Nrf2 and synthesis of GCLC and glutathione

109 Suppl 2 (2001): S122-34

Extensive data indicate that NF-B activity is significantly elevated in the lungs of Gprc5a -ko mice and MTEC-KO cells (mouse lung epithelial cells lacking Gprc5a) when compared to wild-type (WT) counterparts [28, 37]

doi: 10.1016/j.ijbiomac.2024.129793 25

Related Past, Ongoing, and Recent Research Funded by SERDP: ER19-1408 Analysis of Fate of PFAS during Incineration ER22-7470 Development and Application of Injectable Fuels/Adjuncts for In Situ Treatment of PFAS and Co-Occurring Chemicals in Source Areas by Smoldering Combustion 12.5 Air Treatment Technologies PFAS vapors or particles can be generated during any activity that involves PFAS or materials containing PFAS