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Proc Natl Acad Sci USA 103:97389743 Hu X, Xu Z, Xu W, Li J, Zhao N, Zhou Y (2015) Application of -aminobutyric acid demonstrates a protective role of polyamine and GABA metabolism in muskmelon seedlings under Ca(NO 3 ) 2 stress

This boosts fat burning and reduces blood cholesterol

While direct clinical evidence is still developing, the potential for interaction exists

[3] Structurally it descends from oxyntomodulin, a naturally occurring gut hormone that itself activates both receptors, and it carries a C18 fatty-acid chain that extends its half-life enough to support once-weekly subcutaneous administration in trial protocols