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These disorders are uncommon, but there are considerable data to show that the hypothalamopituitaryadrenal axis is overactive, or in some circumstances underactive, in more common situations including depressive illness and septic shock

Neuroimage (2012) 59:32226.10.1016/j.neuroimage.2011.10.090 212 MillerAHMaleticVRaisonCL

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It has been approved for the treatment of toxic liver damage, acute and chronic hepatitis, and abnormal liver function in fatty liver disease

Moreover, disruption in the striatal circuits has been found to promote the formation of habits and compulsive eating patterns (24)