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These bound phenolics need to be hydrolysed by enzymes or microbes in the stomach or pre-treated via techniques like fermentation, soaking, or germination in order to be released because they are not bio-accessible in their natural state (Jiang et al., 2023)

It is not an allergy but a metabolism problem of histamine so it may make a flare up after consuming high histamine foods or foods that trigger the release of histamine

Cooper GJ, Chan YK, Dissanayake AM, Leahy FE, Keogh GF, Frampton CM

This study established CagriSema as the most effective pharmacotherapy for obesity reported in any Phase 3 trial

Repression of IFN- expression by peroxisome proliferator-activated receptor