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Involvement of AtNAP1 in the regulation of chlorophyll degradation in Arabidopsis thaliana

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While current clinical and basic evidence strongly supports ferroptosis as a key contributing mechanism in periodontitis progression, the extent of its role relative to classical pathogenic factors such as dysbiosis and immune dysregulation, as well as its causal temporality in the natural history of the disease, remains unclear

However, preclinical and clinical investigations performed in order to investigate the utility of this combinatory drug strategy in cancer (i.e., HMGCR inhibitors plus SREBP inhibitors), are still a pharmacological challenge