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Cycle length and breaks AOD-9604 protocols require structured cycling to maintain effectiveness and avoid potential receptor downregulation

Because B12 vitamin is bound to amino acids (found in protein foods) and is only released when certain enzymes and stomach acids are present, its possible to consume enough but still remain somewhat deficient

It binds to plasma proteins and is transported to tissues

The bottleneck is cellular NAD+ availability

Since the liver is critical in manufacture and detoxification of hormones, this could explain a link between women suffering heavy periods and vitamin B12 deficiency and hormone imbalance