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Some animal studies, such as one involving a segmental bone defect in rabbits (Sebecic et al., 1999), explored its local application

In a study by Calero Preciado et al

For competitive athletes, IGF-1 and its analogs, including LR3, are banned at all times, in and out of competition, under Section S2 of WADA's Prohibited List (Peptide Hormones, Growth Factors, Related Substances and Mimetics)