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doi: 10.1038/nrrheum.2011.121

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John: Yeah, but they say 1.5 is enough anyway

205 Obesity induced by diet can also trigger the accumulation of PMN-MDSCs, leading to Fas/FasL-mediated apoptosis of tumor-infiltrating CD8 + T cells and causing resistance to immunotherapy in breast cancer treatment

Gene Expression Modulation Transcriptomic analyses in cellular models have shown that GHK-Cu influences expression of a remarkably wide set of genes, with reported effects on pathways involved in: Extracellular matrix remodeling DNA repair Antioxidant response Inflammatory signaling Stem cell signaling markers This broad transcriptional footprint has been one of the most studied aspects of GHK-Cu in recent years