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These results suggest improvement in insulin sensitivity, and moreover, no additional side effects to those found with placebo were observed in T1D, meanwhile in T2D patients oedema, jaw pain and arthralgias were 4 % lower than previous reports [276, 277]

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Vitamin B12 Deficiency and Management During Pregnancy In addition to anaemia, symptoms of vitamin B12 deficiency may include: Fatigue Breathlessness Nervous system symptoms such as numbness, tingling or poor balance Poor concentration or memory Paleness Mood changes, including low mood, anxiety or disrupted sleep Some women are more susceptible to vitamin B12 deficiency than others

Importantly, these effects occurred at rates similar to placebo groups, suggesting that many cases represented background occurrence rather than treatment-specific effects