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Among them, C1-27 was one of the most potent GSTO1 inhibitors (Fig

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It is newly reported that iron is correlated with parkinsonism symptoms in a PD mouse model with mutation in Pla2g6 gene (phospholipase A2 group VI), and that iron-catalyzed lipid oxidation modification reduces glutathione peroxidase 4 activity and content 8 , which is related closely to PD