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Similarly, MitoQ, a mitochondria-directed ubiquinone derivative, demonstrates protective effects in lung injury models by suppressing mtROS, decreasing proinflammatory cytokine secretion, and inhibiting TGF-/NOX4 and PDGF/ROCK signaling pathways (142, 143)

Use of the arginine-depleting agent pegylated arginine deiminase ADI-PEG20 in GBM can increase nitric oxide (NO) synthesis and produce cytotoxic pernitrite, increasing the sensitivity of tumor cells to ionizing radiation and significantly enhancing the effect of radiotherapy on GBM

Prevalence of anti-adeno-associated virus immune responses in international cohorts of healthy donors

After weighing, tissues were instantly placed in BIOPS buffer (calcium-EGTA (10 mM), free calcium (0.1 M), imidazole (20 mM), taurine (20 mM), morpholineethanesulfonic acid (50 mM), dithiothreitol (DTT, 0.5 mM), MgCl 2 (6.56 mM), ATP 5.77 (mM), phosphocreatine (15 mM)