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Moreover, EP supplementation ameliorated gut dysbiosis induced by high-fat diet, through the increase of short-chain fatty acid (SCFA)-producing bacteria and gut-barrier-protective microbe, and the reduction of endotoxin-producing bacteria [70]

Additional research is needed to elucidate the mechanisms that control holo-TC homeostasis in the normal population and in pathologies that alter vitamin B 12 transport and utilization

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It includes: A probation for three to five years