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18 Combined treatment

Incoming cystine is subsequently converted to cysteine, which serves as a substrate for GSH synthesis ( As a member of the glutathione peroxidase family, GPX4 is the first identified core suppressor of ferroptosis ( Figure 2 )

coli cell paste in a soluble fraction and can be purified through, e.g., affinity chromatography and/or size exclusion

Additionally, as a functional ligand of multiple receptors including LDLR, LDL receptor-related protein (LRP) and heparan sulfate proteoglycans (HSPG), Apo E facilitates the clearance of TRL particles, especially VLDL, VLDL and CM remnant particles, and regulates plasma cholesterol and TG levels 13,57

Stroke 34 , 17041709 (2003)