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There is some evidence that an injection of local anaesthetic and steroid can help those who do not respond to the 4 Rs or have an underlying metabolic issue, but a simple injection will not correct the primary cause of the nerve compression

Specifically, the leakage of electrons from mitochondrial ETC complexes gives rise to ROS, which can subsequently react with ferrous ions (Fe 2+ ) to generate OH radicals [89]

However, a role in innate immunity has also been documented

Peran utamanya adalah melindungi sel dari stres oksidatif dan mendukung banyak proses metabolisme, terutama di hati