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10.1038/s41467-020-20141-z 66

Goitrogens suppress the thyroid gland by suppressing the release of thyroid hormone, changing the way thyroid hormone gets produced in the body, and suppressing the absorption of iodine

In mice fed a high-fat diet, administration of hesperidin altered the intestinal microbiota composition, and thus mitigating liver damage and lipid accumulation [29]

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AF itself can induce changes in glucose, lipid and ketone metabolism, mitochondrial function and myofibrillar energetics (as part of a process referred to as metabolic remodelling), which can all contribute to atrial dysfunction