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Unsupervised clustering of scRNA-seq profiles identified 59 cell clusters, which were annotated to 10 cell types based on marker gene identification, lineage marker genes, and mapping to single-cell databases (Figure 1B, Supplemental Figure 1, BE, and Supplemental Table 3)

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This study reveals the potential of iguratimod in treating SS by inhibiting TEC function, offering a treatment strategy distinct from traditional kinase inhibitors