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The ongoing presence of uric acid crystals in and around the joint can lead to destruction of the joint and the soft tissues around it

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Statements Author contributions X-YJ and D-DW contributed to conception and design of the study

In particular, K-F rings due to secondary copper overload may be seen in primary biliary cirrhosis, intrahepatic cholestasis, or chronic hepatitis.23,24 Another ophthalmologic finding of Wilsons is deposits of copper in the anterior and posterior lens capsule called a sunflower cataract.25 These, too, do not interfere with vision and can resolve with chelation therapy