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Regulatory status and legality 2

Trastuzumab deruxtecan (T-DXd/Enhertu ) received FDA approval in 2019 for treating adults with HER2-positive breast cancer that is metastatic or unresectable and who have received two or more prior HER2-targeted therapies

Reasons include: reliance on animal studies anecdotal reports limited human data commercial marketing Scientific conclusions should rely primarily on peer-reviewed evidence

Hematocrit, reticulocyte count, Vitamin B12, folate and iron levels should be obtained prior to treatment

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