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Description

In addition, cocaine activates the SrcPDGFR-NF-B pathway, which enhances CXCL10 [chemokine (C-X-C motif) ligand-1] secretion

Furthermore, TMAO promotes endoplasmic reticulum stress responses within podocyte cellular compartments via IRE1 and PERK pathway activation architectures, culminating in amplified production of inflammatory cytokine arsenals and accelerated apoptotic cell death trajectories (Pan et al., 2023)