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If the peptide restrictions are reversed through formal FDA rulemaking, compounding pharmacies would be legally allowed to prepare those peptides, but only as traditional, patient-specific compounded drugs, not as mass-market or FDA-approved therapies. If the peptides are formally added to the 503A bulk list, he says, pharmacies would have to follow the traditional 503A compounding rules

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In addition to their intrinsic capabilities to refresh NP cellularity, NPPCs also induce significant phenotypical changes in surrounding NPCs through establishing an intricate cell-cell communication network, during which they could export some of their progenitor-like properties into differentiated NPCs for maintaining their cellular hemostasis in the NP microenvironment 12

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