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Weight regain after discontinuation occurs if caloric intake increases back to pre-diet levels, which is a dietary adherence issue, not a metabolic rebound from stopping the injections

History of serious hypersensitivity reaction (anaphylaxis, angioedema) to GLP-1 receptor agonists

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[2] When to Seek Further Medical Advice About B12 Patients should maintain regular contact with their GP or healthcare team throughout B12 treatment, but certain situations warrant urgent medical review