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Thyroid 8 , 3741 (1998)

The same MAP2 proteoform (MAP2_HPPE_17) which exhibited depletion in frail brain was enriched with resilience

By performing co-culture experiments between wild-type or UBE2I KD cancer cells and CCA-derived cancer-associated fibroblasts (CAFs), human endothelial cells or monocytes, we have unveiled the impact of SUMOylation in the crosstalk between CCA cells and the TME