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Region-focused multi-view transformer-based generative adversarial network for cardiac cine MRI reconstruction

This work was supported by R35HL139726 (ESN), R01HL156670 (CCS), K24HL150630 (CCS), and 5R01HL157973 (SF)

however, for toxicity prediction, cumulative drug exposure, particularly cumulative AUC over the treatment course, appears more informative than isolated peak or trough measurements ( Bayesian forecasting represents a further refinement, combining population pharmacokinetic models with individual patient covariates and measured drug concentrations to generate patient-specific pharmacokinetic parameter estimates and optimize dosing

However, resistance mechanisms arise during the treatment with daratumumab, creating the necessity for new therapies