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Physical Symptoms of Vitamin B12 Deficiency Fatigue and weakness Pale skin Shortness of breath Nerve problems Mouth ulcers Digestive issues Vision problems Mobility difficulties Cognitive Symptoms of Vitamin B12 Deficiency Peripheral Neuropathy Cognitive Disturbances Memory Problems Reversible Dementia Confusion Decreased Problem Solving Psychiatric Symptoms of Vitamin B12 Deficiency Depression Anxiety Intrusive Thoughts Irritability Psychosis Inattention Insomnia Panic attacks Treatment of Vitamin B12 Deficiency It has been observed that oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms

10.1186/s13287-018-1123-7 111 MazzarellaL.DusoB

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Vitamin B12 may be more effective than nortriptyline in improving painful diabetic neuropathy

No, semaglutide is FDA-approved only for subcutaneous injection and is not formulated or studied for intravenous use