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J Med Plants 9(3):118122 Periasamy VS, Athinarayanan J, Alshatwi AA (2016) Anticancer activity of an ultrasonic nanoemulsion formulation of Nigella sativa L

Abstract Cyanocobalamin (CNCbl), a medicinal form of vitamin B 12 , is resistant to glutathione (GSH), and undergoes intracellular processing via reductive decyanation producing the Co(II)-form of Cbl (Cbl(II)) mediated by the CblC-protein

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Like basal-like tumours, it is triple negative (ER-, PR-, HER2-) but differs in having low Ki67 expression and elevated markers associated with epithelial-mesenchymal transition, indicating a distinct biological behaviour (142, 143)