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Description

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References Magro CM, Crowson AN, Mihm MC

Once activated, TRI functions as a tyrosine receptor kinase through phosphorylation, thereby activating the RhoA/Grb2/ERK signaling pathway (255) as well as p38 MAPK and JNK via the TNF receptor-associated factor 6 and TGF--activating enzyme-1/M3K7 pathways (256, 257)