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Reprogramming of lipid metabolism in the treatment of COPD Reprogramming of lipid metabolism is involved in the pathogenesis of COPD through immune cells Immune cells are distributed throughout immune organs and various parts of the body, playing roles in maintaining tissue and organ homeostasis, as well as resisting pathogen invasion

(PubMed) Hoen WP, Lijmer JG, Duran M, Wanders RJ, van Beveren NJ, de Haan L

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Other factors implicated in early development of mDA neurons include Wnt1, En1, En2, Nurr1, Pitx3, Lmx1B, Foxa2, and Pax5 (Maxwell and Li, 2005)

This results in defective complexes I and II, which in turn diminishes the potential transfer of electrons in the respiratory chain, leading to an increase in ROS