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133 Melatonin protects lipids, proteins, and nuclear DNA from oxidative damage

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The crude extract (0.003 and 0.009 g/ml) also exhibited vasodilatory effect, as it inhibited both KCl- and phenylephrine-induced contractions in rat isolated thoracic aortic rings (Ng et al., 2013)

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Additionally, in association with or independently of oxidative stress, non-dividing cells such as neurons can accumulate DSBs from transcription 68 but also through abnormal activity and cell cycle reentry 37,38,68,86,87