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The use of assisted reproductive technologies (ART) such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) can bypass some of the natural selection mechanisms that would prevent sperm with damaged DNA from fertilizing an egg, potentially leading to long-term consequences for the offspring

The overall structure of Rv1098c displays a symmetric homo-tetramer conformation, which shares significant structural similarity with other members of the class II fumarase superfamily [288] (Fig

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[DOI] [PubMed] [Google Scholar] 101.Wischmeyer P, Kahana M, Wolfson R, Ren H, Musch MM, Chang EB