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Studies have shown that it can reduce the expression of pro-inflammatory cytokines such as Tumour Necrosis Factor-alpha (TNF-) and Interleukin-6 (IL-6)

TA might be involved in kidney damage, causing TRPV4 dysfunction by decreasing the expression of MAP7D1

This distinction is central to its research value: it allows scientists to study CNS-specific activity in isolation, without the confounding hormonal effects of a full ACTH molecule

While vitamin B12 deficiency can lead to the underdevelopment of the brain in early life, it can also lead to severe symptoms in adulthood, ranging from dementia, memory loss and cognitive/intellectual decline

MitoSOX Red indicator and PI were detected using the TRITC filter (Ex/Em: 396/610 nm) and Texas Red (Ex/Em:560/630), respectively, while Hoechst was detected using HOECHST 33342 filter (Ex/Em: 353/483)