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Based on the scientific evidence available for mitochondria-relevant nutraceuticals, this article presents examples of frequent medical conditions, which require protective measures targeted on mitochondria as a holistic approach following advanced concepts of predictive, preventive, and personalized medicine (PPPM/3PM) in primary and secondary care

In Phase 2 detoxification, various enzymes act directly on the toxic substances partially degraded and processed in Phase 1, such as heavy metals and organo-toxins, by binding them with protective compounds, thereby either inactivating the toxins

10.3390/antiox9080768 13

Proteins produced in vitro were subjected to interaction assays for 2 hours at 4C under mild rotation with Drosophila nuclear extracts or recombinant protein produced and purified in vitro

This is specifically pertinent if the temperature of hot water is higher than the body temperature