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For example, chelating agents may induce toxicity by binding with other metal ions while off-target effects make copper regulation using copper ion carriers difficult, thus additional studies on how to regulate copper levels are required (180)

A number of BPC-157 animal studies examined the peptide alongside L-arginine or the nitric-oxide-synthase inhibitor L-NAME

Although they signed consent forms agreeing to take the drug, they were reportedly not aware that its effects were being tested

Khasnavis S, Belliveau T, Arnsten A, Fesharaki-Zadeh A