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Footnotes AUTHOR CONTRIBUTIONS All authors contributed to the study concept & design, data acquisition & analysis, and to drafting manuscript & figures

PT-141: nausea, flushing, mild headache

IGF-1 LR3 acts at the endpoint A large family of research peptides GHRH analogs such as tesamorelin, and growth-hormone secretagogues/ghrelin-receptor agonists work by increasing endogenous GH pulses, which in turn raise the bodys own IGF-1 through the intact, self-regulating cascade

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While it can improve cognitive function indirectly by removing the brain fog caused by anxiety and stress, it does not upregulate BDNF or increase neurogenesis like a true nootropic (Semax) does