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Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment

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Interleukin-10 prevents pathological microglia hyperactivation following peripheral endotoxin challenge

Each compound was used at a final concentration of 5 M

Additionally, serine restriction or SHMT inhibition hampers T cell proliferation and pathogen clearance in murine infection models, though this effect can be reversed by exogenous nucleotide supplementation [141]