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Nausea from tirzepatide peaks 2472 hours post-injection and typically resolves within 48 weeks at a stable dose as GLP-1 receptor density downregulates in the gut

Untreated pernicious anaemia also carries a greater risk of developing stomach cancer

Frequency and administration will vary based on individual needs and goals

For some women, monthly pain is minor

5 Once steady state is reached, the washout period for AJOVY is similar for monthly and quarterly dosing (~5-6 half-lives) 6 Washout period defined as time until plasma concentrations of AJOVY are below a clinically relevant concentration and thus considered eliminated