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Citation: Li, S., Huang, Y., Zhang, R., Li, S., Wang, T., Zhang, K., & Zhou, Y

38 induced AD in Sprague Dawley rats by oral administration of 175 mg/kg of AlCl 3 for 25 days to study the protective effect of ononin treatment on AD (Table 1)

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The study found that the enforced expression of MT-1E p.C36C stabilized glucose metabolism and led to a reduction in body weight, whereas the expression of MT-1E p.C36Y had the opposite effect [109]