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Mol Neurobiol 54:54405448 [DOI] [PMC free article] [PubMed] [Google Scholar] Lizrraga KJ, Lang AE (2022) Vitamins B6 and B12, levodopa, and their complex interactions in patients with Parkinsons disease

First, in the public healthcare system, the mean age of tested individuals was 54 years

Thats not what we do here

The applicant also noted that after propensity-score weighting, the study considered all differences in the reason(s) for cystoscopy to be negligible and collected data from a single institution's integrated electronic medical record

But people can get blemishes from flu shots, so there is no direct correlation that B12 causes blemishes. Unfortunately though, theres no way to know beforehand if B12 will cause a breakout