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Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning

Br J Cancer 117(5):648-655, 2017

Phase II Detoxification The liver attaches glutathione to toxic molecules through a process called conjugation, making them water-soluble and ready for excretion

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(iv) One clue to toxicant-induced AD could be the finding that mercury and iron co-localize in locus ceruleus neurons and in hippocampal white matter oligodendrocytes in PD brains (Figure 14), given the early involvement of the hippocampus in AD, the suspected role of iron in a variety of neurodegenerative disorders (28), and the realization that synergistic interactions between intracellular toxic metals are common (12)