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A novel UPLC-MS metabolomic analysis-based strategy to monitor the course and extent of iPSC differentiation to hepatocytes

We selected two additional putative ArfGAP1 phosphorylation sites (S284, T291) for further analysis, since pS284 was identified by a prior study [17] and also lies within the GAP-F5 fragment, whereas the known phospho-site T291 is adjacent to T292 that makes it challenging to assign precise phospho-site localization within a single phospho-peptide

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