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Tremella fuciformis polysaccharides (TFP) exhibited strong microbiota-regulating activity by increasing SCFA-producing bacteria and Lactobacillus , while simultaneously enhancing tight junction protein expression and reducing oxidative stress

Tangier disease, characterized by severe HDL deficiency and cholesterol ester accumulation in tissues, is caused by mutations in the ABCA1 gene, impairing cellular cholesterol efflux and reverse cholesterol transport

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Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials