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Additionally, there is a negative association between cerebrospinal fluid lactate levels and Tau protein levels, suggesting a possible connection between anaerobic metabolic shifts and cytoskeletal abnormalities

Located within the mitochondrial matrix, the TCA cycle produces the reduced cofactors NADH and FADH_2, which serve as the primary electron donors for the electron transport chain (ETC)

The historically important question, which has been the subject of frequent discussions, is whether oxidative stress is the primary cause or secondary consequence of the disease

Each one of these tiny cells requires glutathione to shield it from damage

Glycine and mitochondrial function and oxidative phosphorylation The glycine cleavage system (GCS) is an important metabolic pathway in mitochondria