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Metal ions, such as iron, manganese, copper, zinc, etc., play crucial roles in various physiological processes in the central nervous system (CNS), including energy metabolism, protein synthesis, DNA replication, membrane protein construction, myelin and neurotransmitter synthesis, and so on

When reported, the TQ content was 1.5% to 3.0%

doi: 10.1016/j.ejphar.2023.175903 293 ZhaoH.WuL.YanG.ChenY.ZhouM.WuY.et al

The presence of KGN did not show an obvious effect on the mechanical properties of the hydrogels, in which there were no significant differences between PMI and PKG hydrogels in fracture stress and strain

While the renal biochemistry values were significantly increased at the end of the study, this finding would be expected for any CHF patient after chronic diuretic administration