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In retina facing high oxidative burden from light exposure and metabolism, enhanced antioxidant defenses critical for long-term photoreceptor and RPE survival

Furthermore, methods to study MLOs must be carefully selected and amended based on the stage of the MLO life

[49] A cysteine-rich domain at the N-lobe of GPC3 has been identified to form a Wnt-binding hydrophobic groove including phenylalanine-41 that interacts with Wnt