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Mitochondrial dysfunction, a key feature of AD, further exacerbates ROS production, impairs ATP generation, disrupts calcium homeostasis, and ultimately induces neuronal apoptosis (Butterfield and Halliwell, 2019)

BMC Public Health 22, 1371

It is also banned under WADA anti-doping rules

The net effect: adipocytes become metabolically sluggish, oxidizing less fat, storing more energy, and resisting signals that would normally promote energy expenditure

Emerging research suggests that individuals with low levels of Vitamin B12 may experience fatigue and slower metabolism, which can hinder weight management efforts making supplementation a supportive step for those with a diagnosed deficiency