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Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia

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A recent in vitro study identified numerous clusters of endothelial, epithelial, and mesothelial cells as well as hematopoietic cells including macrophages, monocytes, neutrophils, dendritic cells, natural killer cells, and lymphocytes with different profiles

Its a regulatory protein that moderates the inflammatory response.[ref] Ro60 is an RNA-binding protein found in almost all animals and even in single-celled eukaryotes

Studies have shown that asymptomatic individuals with hyperuricemic already exhibit subclinical inflammation (e.g., elevated IL-6 and CRP), whereas acute gout flares are characterized by significant increases in IL-1 and S100A8/A9 levels, which may serve as distinguishing biomarkers (Ohashi et al., 2024