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38 Collectively, all these discoveries have contributed not only to our understanding of the biological aging process, but also allowed to develop rationale intervention strategies to target molecular hallmarks of this process and biomarkers to quantify biological aging status, aiming to achieved healthy lifespan extension with precise and multitargeted approaches

K., van Bruggen R

To model the metabolic zonation pattern, the linear zonation pattern has been used as exact distribution profiles of metabolic parameters such as GSH are not known

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Survodutide and orforglipron represent additional pipeline compounds that may eventually provide even more options