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On the basis of microscopic reversibility of enzymatic reactions, the enzyme-catalyzed oxidation of roGFP2(SH) 2 by GSSG or GSSR follows the reverse reaction of mechanism (iii)

High titers of antibody against thyroglobulin (TG) and thyroid peroxidase (TPO) are present in most patients with Hashimoto's thyroiditis(17), and TPO antibodies are complement fixing and may be cytotoxic